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indirect
PMID: 15199958
The activated factor C activates factor B, which converts the
proclotting enzyme into the clotting enzyme, which in turn
converts coagulogen into an insoluble coagulin gel
indirect
PMID: 15199958,8808632
In the embryo, a proteolytic cascade that
includes three proteases (gastrulation defective, snake, and
easter) cleaves a cytokine-like protein, Spaetzle, as a ligand for
dToll
indirect
PMID: 15199958,3512266
These serine protease zymogens are autocatalytically
activated by LPS and b-1,3-glucans, respectively.
PMID: 15199958,11130078
Furthermore, in TLR-9, which is essential for
recognizing and triggering the inflammatory response to bacterial
DNA containing CpG sequences, long inserts are
present in repeat-2, repeat-5, and repeat-8 after position 10
indirect
PMID: 15199958
The activated factor C activates factor B, which converts the
proclotting enzyme into the clotting enzyme, which in turn
converts coagulogen into an insoluble coagulin gel
indirect
PMID: 15199958,8808632
In the embryo, a proteolytic cascade that
includes three proteases (gastrulation defective, snake, and
easter) cleaves a cytokine-like protein, Spaetzle, as a ligand for
dToll
PMID: 15199958,10359581
TLR-4 forms a complex with an accessory protein
MD-2, and it triggers the innate immune response to LPS
indirect
PMID: 15199958,7822328
These serine protease zymogens are autocatalytically
activated by LPS and b-1,3-glucans, respectively.
indirect
PMID: 15199958,1209870,11812988
During
infection, the cleaved form of Spaetzle is produced
through another proteolytic cascade, one that includes Persephone,
a newly identified serine protease.
indirect
PMID: 15199958,12359879
Overexpression of
peptidoglycan-recognition protein-LE, a receptor for the
diaminopimelic acid-type peptidoglycan, leads to the activation
of prophenoloxidase cascade in Drosophila larvae
PMID: 15199958,10359581
TLR-4 forms a complex with an accessory protein
MD-2, and it triggers the innate immune response to LPS
PMID: 15199958,12359879
Overexpression of
peptidoglycan-recognition protein-LE, a receptor for the
diaminopimelic acid-type peptidoglycan, leads to the activation
of prophenoloxidase cascade in Drosophila larvae
indirect
PMID: 15199958
The activated
factor G activates the proclotting enzyme directly
indirect
PMID: 15199958
The activated factor C activates factor B, which converts the
proclotting enzyme into the clotting enzyme, which in turn
converts coagulogen into an insoluble coagulin gel
PMID: 15199958
The
horseshoe crab coagulation cascade promotes prophenoloxidase
activation through the non-enzymatic interaction of factor
B or through the interaction of proclotting enzyme with hemocyanin.
indirect
PMID: 15199958,8808632
In the embryo, a proteolytic cascade that
includes three proteases (gastrulation defective, snake, and
easter) cleaves a cytokine-like protein, Spaetzle, as a ligand for
dToll
PMID: 15199958,8808632
In the embryo, a proteolytic cascade that
includes three proteases (gastrulation defective, snake, and
easter) cleaves a cytokine-like protein, Spaetzle, as a ligand for
dToll