_enti_e7
_enti_e8
_enti_e1
_enti_e9
_enti_e10
_enti_e4
_enti_e3
_enti_e2
_enti_e55
_enti_e53
_enti_e59
_enti_e52
_enti_e50
_enti_e51
_enti_e56
_enti_e54
_enti_e61
_enti_e58
_enti_e57
_enti_e60
_enti_e62
g2_fact_g2
g1_fact_g14
g1_fact_g1
g2_fact_g12
g2_fact_g13
p1_propro_p1
PMID:18160296
Ligand recognition, by TLR homo- or hetero-dimers, induces signalling cascades mediated through intracellular adaptors, including myeloid differentiation primary response gene 88 (MyD88) and TIR-domain-containing adaptor-inducing interferon-beta (TRIF), which result in the activation of several transcription factors, such as NF-kappaB and interferon-regulatory factor 3 (IRF3).
c1 cso30:c:InputProcess connector
c2 cso30:c:InputProcess connector
c3 cso30:c:OutputProcess connector
p2_propro_p2
PMID:18160296
Ligand recognition, by TLR homo- or hetero-dimers, induces signalling cascades mediated through intracellular adaptors, including myeloid differentiation primary response gene 88 (MyD88) and TIR-domain-containing adaptor-inducing interferon-beta (TRIF), which result in the activation of several transcription factors, such as NF-kappaB and interferon-regulatory factor 3 (IRF3).
c4 cso30:c:InputProcess connector
c5 cso30:c:InputProcess connector
c6 cso30:c:OutputProcess connector
p3_propro_p3
PMID:18160296
Ligand recognition, by TLR homo- or hetero-dimers, induces signalling cascades mediated through intracellular adaptors, including myeloid differentiation primary response gene 88 (MyD88) and TIR-domain-containing adaptor-inducing interferon-beta (TRIF), which result in the activation of several transcription factors, such as NF-kappaB and interferon-regulatory factor 3 (IRF3).
c7 cso30:c:InputProcess connector
c8 cso30:c:InputProcess connector
c9 cso30:c:OutputProcess connector
p4_propro_p4
PMID:18160296
Ligand recognition, by TLR homo- or hetero-dimers, induces signalling cascades mediated through intracellular adaptors, including myeloid differentiation primary response gene 88 (MyD88) and TIR-domain-containing adaptor-inducing interferon-beta (TRIF), which result in the activation of several transcription factors, such as NF-kappaB and interferon-regulatory factor 3 (IRF3).
c10 cso30:c:InputProcess connector
c14 cso30:c:InputAssociation connector
c11 cso30:c:OutputProcess connector
p5_propro_p5
PMID:18160296
Ligand recognition, by TLR homo- or hetero-dimers, induces signalling cascades mediated through intracellular adaptors, including myeloid differentiation primary response gene 88 (MyD88) and TIR-domain-containing adaptor-inducing interferon-beta (TRIF), which result in the activation of several transcription factors, such as NF-kappaB and interferon-regulatory factor 3 (IRF3).
c12 cso30:c:InputProcess connector
c15 cso30:c:InputAssociation connector
c13 cso30:c:OutputProcess connector
p6_propro_p6
PMID: 18160296, 15668126
This activity is mediated by CTLD 48 of the receptor, which bind terminal mannose, fucose or N-acetyl glucosamine and is responsible for microbial recognition.
PMID: 18160296
A variety of endogenous and exogenous ligands have been described for the various domains of the MR, including the Ca2+-dependent recognition of carbohydrates.
c16 cso30:c:InputProcess connector
c17 cso30:c:InputProcess connector
c93 cso30:c:InputAssociation connector
c22 cso30:c:OutputProcess connector
p7_propro_p7
PMID: 18160296, 15668126
This activity is mediated by CTLD 48 of the receptor, which bind terminal mannose, fucose or N-acetyl glucosamine and is responsible for microbial recognition.
PMID: 18160296
A variety of endogenous and exogenous ligands have been described for the various domains of the MR, including the Ca2+-dependent recognition of carbohydrates.
c18 cso30:c:InputProcess connector
c20 cso30:c:InputProcess connector
c94 cso30:c:InputAssociation connector
c23 cso30:c:OutputProcess connector
p8_propro_p8
PMID: 18160296, 15668126
This activity is mediated by CTLD 48 of the receptor, which bind terminal mannose, fucose or N-acetyl glucosamine and is responsible for microbial recognition.
PMID: 18160296
A variety of endogenous and exogenous ligands have been described for the various domains of the MR, including the Ca2+-dependent recognition of carbohydrates.
c19 cso30:c:InputProcess connector
c21 cso30:c:InputProcess connector
c95 cso30:c:InputAssociation connector
c24 cso30:c:OutputProcess connector
p9_propro_p9
PMID: 18160296, 2828085
We now know that mannan can be recognised by several mannose-receptors, such as DC-SIGN, and is often contaminated with other carbohydrates involved in fungal recognition, such as beta-glucan.
PMID: 18160296, 15659060
DC-SIGN recognises carbohydrates, such as high-mannose structures, in a Ca2+-dependent fashion with specificity being achieved through unique interactions with its ligands and tetramerisation of the receptor.
c25 cso30:c:InputProcess connector
c26 cso30:c:InputProcess connector
c99 cso30:c:InputAssociation connector
c27 cso30:c:OutputProcess connector
p10_propro_p10
PMID: 18160296,15668126, 15155616, 17020928
In response to fungi, the MR can induce NF-kappaB activation and the production of several cytokines, including IL-12, IL-8, IL-1beta, IL-6 and granulocytemacrophage colony-stimulating factor (GM-CSF), and can also enhance MR shedding.
PMID: 18160296
A variety of endogenous and exogenous ligands have been described for the various domains of the MR, including the Ca2+-dependent recognition of carbohydrates.
c29 cso30:c:InputProcess connector
c28 cso30:c:InputProcess connector
c96 cso30:c:InputAssociation connector
c30 cso30:c:OutputProcess connector
p11_propro_p11
PMID: 18160296, 15668126, 15155616, 17020928
In response to fungi, the MR can induce NF-kappaB activation and the production of several cytokines, including IL-12, IL-8, IL-1beta, IL-6 and granulocytemacrophage colony-stimulating factor (GM-CSF), and can also enhance MR shedding.
c31 cso30:c:InputAssociation connector
c32 cso30:c:InputProcess connector
c33 cso30:c:OutputProcess connector
p12_propro_p12
PMID: 18160296,15668126, 15155616, 17020928
In response to fungi, the MR can induce NF-kappaB activation and the production of several cytokines, including IL-12, IL-8, IL-1beta, IL-6 and granulocytemacrophage colony-stimulating factor (GM-CSF), and can also enhance MR shedding.
c40 cso30:c:InputAssociation connector
c46 cso30:c:InputAssociation connector
c34 cso30:c:OutputProcess connector
p13_propro_p13
PMID: 18160296,15668126, 15155616, 17020928
In response to fungi, the MR can induce NF-kappaB activation and the production of several cytokines, including IL-12, IL-8, IL-1beta, IL-6 and granulocytemacrophage colony-stimulating factor (GM-CSF), and can also enhance MR shedding.
c41 cso30:c:InputAssociation connector
c47 cso30:c:InputAssociation connector
c35 cso30:c:OutputProcess connector
p14_propro_p14
PMID: 18160296,15668126, 15155616, 17020928
In response to fungi, the MR can induce NF-kappaB activation and the production of several cytokines, including IL-12, IL-8, IL-1beta, IL-6 and granulocytemacrophage colony-stimulating factor (GM-CSF), and can also enhance MR shedding.
c42 cso30:c:InputAssociation connector
c48 cso30:c:InputAssociation connector
c36 cso30:c:OutputProcess connector
p15_propro_p15
PMID: 18160296,15668126, 15155616, 17020928
In response to fungi, the MR can induce NF-kappaB activation and the production of several cytokines, including IL-12, IL-8, IL-1beta, IL-6 and granulocytemacrophage colony-stimulating factor (GM-CSF), and can also enhance MR shedding.
c43 cso30:c:InputAssociation connector
c49 cso30:c:InputAssociation connector
c37 cso30:c:OutputProcess connector
p16_propro_p16
PMID: 18160296,15668126, 15155616, 17020928
In response to fungi, the MR can induce NF-kappaB activation and the production of several cytokines, including IL-12, IL-8, IL-1beta, IL-6 and granulocytemacrophage colony-stimulating factor (GM-CSF), and can also enhance MR shedding.
c44 cso30:c:InputAssociation connector
c50 cso30:c:InputAssociation connector
c38 cso30:c:OutputProcess connector
p17_propro_p17
PMID: 18160296,16000387
However, with certain fungi, such as Pneumocystis, the MR might have an immunosuppressive role, inhibiting the production inflammatory cytokines, such as tumour necrosis factor (TNF).
c45 cso30:c:InputAssociation connector
c51 cso30:c:InputInhibitor connector
c39 cso30:c:OutputProcess connector
p18_propro_p18
PMID: 18160296, 16341139, 16371356
Although most similar to CLRs with proteinaceous ligands, Dectin-1 recognises beta-1,3-glucans in a calcium-independent fashion through an unknown mechanism and is the major receptor for these carbohydrates on leukocytes.
c52 cso30:c:InputProcess connector
c53 cso30:c:InputProcess connector
c54 cso30:c:OutputProcess connector
p19_propro_p19
PMID: 18160296, 16341139, 17450144
This induces a variety of cellular responses, including the respiratory burst, activation and regulation of phospholipase A2 (PLA2) and cyclooxygenase 2 (COX2), ligand uptake by endocytosis and phagocytosis and the production of several cytokines and chemokines, including TNF, macrophage inflammatory protein 2 (MIP-2), IL-2, IL-10, IL-6 and IL-23.
c58 cso30:c:InputAssociation connector
c144 cso30:c:InputAssociation connector
c55 cso30:c:OutputProcess connector
p20_propro_p20
PMID: 18160296, 16341139, 17450144
This induces a variety of cellular responses, including the respiratory burst, activation and regulation of phospholipase A2 (PLA2) and cyclooxygenase 2 (COX2), ligand uptake by endocytosis and phagocytosis and the production of several cytokines and chemokines, including TNF, macrophage inflammatory protein 2 (MIP-2), IL-2, IL-10, IL-6 and IL-23.
c59 cso30:c:InputAssociation connector
c145 cso30:c:InputAssociation connector
c56 cso30:c:OutputProcess connector
p21_propro_p21
PMID: 18160296, 16341139, 17450144
This induces a variety of cellular responses, including the respiratory burst, activation and regulation of phospholipase A2 (PLA2) and cyclooxygenase 2 (COX2), ligand uptake by endocytosis and phagocytosis and the production of several cytokines and chemokines, including TNF, macrophage inflammatory protein 2 (MIP-2), IL-2, IL-10, IL-6 and IL-23.
c60 cso30:c:InputAssociation connector
c146 cso30:c:InputAssociation connector
c57 cso30:c:OutputProcess connector
p22_propro_p22
PMID: 18160296, 16341139, 17450144
This induces a variety of cellular responses, including the respiratory burst, activation and regulation of phospholipase A2 (PLA2) and cyclooxygenase 2 (COX2), ligand uptake by endocytosis and phagocytosis and the production of several cytokines and chemokines, including TNF, macrophage inflammatory protein 2 (MIP-2), IL-2, IL-10, IL-6 and IL-23.
c72 cso30:c:InputAssociation connector
c81 cso30:c:InputAssociation connector
c73 cso30:c:OutputProcess connector
p23_propro_p23
PMID: 18160296, 16341139, 17450144
This induces a variety of cellular responses, including the respiratory burst, activation and regulation of phospholipase A2 (PLA2) and cyclooxygenase 2 (COX2), ligand uptake by endocytosis and phagocytosis and the production of several cytokines and chemokines, including TNF, macrophage inflammatory protein 2 (MIP-2), IL-2, IL-10, IL-6 and IL-23.
PMID: 18160296,16000387
However, with certain fungi, such as Pneumocystis, the MR might have an immunosuppressive role, inhibiting the production inflammatory cytokines, such as tumour necrosis factor (TNF).
c74 cso30:c:InputAssociation connector
c82 cso30:c:InputAssociation connector
c151 cso30:c:InputInhibitor connector
c75 cso30:c:OutputProcess connector
p24_propro_p24
PMID: 18160296, 16341139, 16862125
Signalling from Dectin-1 is mediated through novel pathways, including an unusual interaction with spleen tyrosine kinase (Syk), which triggers downstream signalling through caspase-recruitment domain 9 (CARD9).
c61 cso30:c:InputProcess connector
c62 cso30:c:InputProcess connector
c63 cso30:c:OutputProcess connector
p25_propro_p25
PMID: 18160296, 16341139, 16862125
Signalling from Dectin-1 is mediated through novel pathways, including an unusual interaction with spleen tyrosine kinase (Syk), which triggers downstream signalling through caspase-recruitment domain 9 (CARD9).
c64 cso30:c:InputProcess connector
c66 cso30:c:InputAssociation connector
c65 cso30:c:OutputProcess connector
p26_propro_p26
PMID: 18160296, 17450144
The CARD9 pathway has been shown recently to induce DC maturation and direct T helper 17 (Th17)-cell responses independently of the TLRs, demonstrating that signalling through Dectin-1 can couple to adaptive immunity directly.
c76 cso30:c:InputAssociation connector
p27_propro_p27
PMID: 18160296, 16341139, 17450144
This induces a variety of cellular responses, including the respiratory burst, activation and regulation of phospholipase A2 (PLA2) and cyclooxygenase 2 (COX2), ligand uptake by endocytosis and phagocytosis and the production of several cytokines and chemokines, including TNF, macrophage inflammatory protein 2 (MIP-2), IL-2, IL-10, IL-6 and IL-23.
c77 cso30:c:InputProcess connector
c143 cso30:c:InputAssociation connector
c78 cso30:c:OutputProcess connector
p28_propro_p28
PMID: 18160296, 16341139, 17450144
This induces a variety of cellular responses, including the respiratory burst, activation and regulation of phospholipase A2 (PLA2) and cyclooxygenase 2 (COX2), ligand uptake by endocytosis and phagocytosis and the production of several cytokines and chemokines, including TNF, macrophage inflammatory protein 2 (MIP-2), IL-2, IL-10, IL-6 and IL-23.
c79 cso30:c:InputProcess connector
c142 cso30:c:InputAssociation connector
c80 cso30:c:OutputProcess connector
p29_propro_p29
PMID: 18160296, 16423983
Dectin-2 possesses cation-dependent mannose and fucose lectin activity with specificity for high mannose structures.
c83 cso30:c:InputProcess connector
c97 cso30:c:InputProcess connector
c85 cso30:c:OutputProcess connector
p30_propro_p30
PMID: 18160296, 16423983
Dectin-2 possesses cation-dependent mannose and fucose lectin activity with specificity for high mannose structures.
c84 cso30:c:InputProcess connector
c98 cso30:c:InputProcess connector
c86 cso30:c:OutputProcess connector
p31_propro_p31
PMID: 18160296, 17050534
The cytoplasmic tail of Dectin-2 appears to associate through a novel interaction with the Fcγ chain, a signalling adaptor associated with several other transmembrane receptors, and can induce TNF and IL-1R antagonist in response to hyphal forms of C. albicans.
PMID: 18160296,16000387
However, with certain fungi, such as Pneumocystis, the MR might have an immunosuppressive role, inhibiting the production inflammatory cytokines, such as tumour necrosis factor (TNF).
c89 cso30:c:InputAssociation connector
c92 cso30:c:InputAssociation connector
c152 cso30:c:InputInhibitor connector
c87 cso30:c:OutputProcess connector
p32_propro_p32
PMID: 18160296, 17050534
The cytoplasmic tail of Dectin-2 appears to associate through a novel interaction with the Fcγ chain, a signalling adaptor associated with several other transmembrane receptors, and can induce TNF and IL-1R antagonist in response to hyphal forms of C. albicans.
PMID: 18160296,16000387
However, with certain fungi, such as Pneumocystis, the MR might have an immunosuppressive role, inhibiting the production inflammatory cytokines, such as tumour necrosis factor (TNF).
c90 cso30:c:InputAssociation connector
c91 cso30:c:InputAssociation connector
c153 cso30:c:InputInhibitor connector
c88 cso30:c:OutputProcess connector
p33_propro_p33
PMID: 18160296, 15659060
DC-SIGN recognises carbohydrates, such as high-mannose structures, in a Ca2+-dependent fashion with specificity being achieved through unique interactions with its ligands and tetramerisation of the receptor.
c100 cso30:c:InputProcess connector
c101 cso30:c:OutputProcess connector
p34_propro_p34
PMID: 18160296, 15096474, 14707091
Of the murine homologues, only SIGNR1 (also termed murine DC-SIGN) and SIGNR3 recognise fungal particles.
c102 cso30:c:InputProcess connector
c103 cso30:c:InputProcess connector
c104 cso30:c:OutputProcess connector
p35_propro_p35
PMID: 18160296, 17462920, 17496896
DC-SIGN can induce intracellular signalling through the Raf-kinase pathway, modulating TLR-mediated responses and inducing higher levels of the immunosuppressive cytokine IL-10.
c105 cso30:c:InputProcess connector
c109 cso30:c:InputAssociation connector
c106 cso30:c:OutputProcess connector
p36_propro_p36
PMID: 18160296, 17462920, 17496896
DC-SIGN can induce intracellular signalling through the Raf-kinase pathway, modulating TLR-mediated responses and inducing higher levels of the immunosuppressive cytokine IL-10.
c108 cso30:c:InputAssociation connector
c107 cso30:c:OutputProcess connector
p37_propro_p37
PMID: 18160296, 16213021
Similar to MBP, these collectins have been proposed to bind directly to cellular receptors, including C1q receptor (C1qRp), signal-regulating protein alpha (SIRPalpha), calreticulin and CD14.
c116 cso30:c:InputProcess connector
c110 cso30:c:InputProcess connector
c118 cso30:c:OutputProcess connector
p38_propro_p38
PMID: 18160296, 16213021
Similar to MBP, these collectins have been proposed to bind directly to cellular receptors, including C1q receptor (C1qRp), signal-regulating protein alpha (SIRPalpha), calreticulin and CD14.
c111 cso30:c:InputProcess connector
c117 cso30:c:InputProcess connector
c119 cso30:c:OutputProcess connector
p39_propro_p39
PMID: 18160296, 16213021
Similar to MBP, these collectins have been proposed to bind directly to cellular receptors, including C1q receptor (C1qRp), signal-regulating protein alpha (SIRPalpha), calreticulin and CD14.
c112 cso30:c:InputProcess connector
c130 cso30:c:InputProcess connector
c120 cso30:c:OutputProcess connector
p40_propro_p40
PMID: 18160296, 16213021
Similar to MBP, these collectins have been proposed to bind directly to cellular receptors, including C1q receptor (C1qRp), signal-regulating protein alpha (SIRPalpha), calreticulin and CD14.
c113 cso30:c:InputProcess connector
c131 cso30:c:InputProcess connector
c121 cso30:c:OutputProcess connector
p41_propro_p41
PMID: 18160296, 11181966
Through unknown mechanisms, SP-A and SP-D can also modulate a variety of host cell functions, such as phagocytosis, cytokine production and the respiratory burst.
c124 cso30:c:InputAssociation connector
c127 cso30:c:InputAssociation connector
c122 cso30:c:OutputProcess connector
p42_propro_p42
PMID: 18160296, 11181966
Through unknown mechanisms, SP-A and SP-D can also modulate a variety of host cell functions, such as phagocytosis, cytokine production and the respiratory burst.
c125 cso30:c:InputAssociation connector
c126 cso30:c:InputAssociation connector
c123 cso30:c:OutputProcess connector
p43_propro_p43
PMID: 18160296
A soluble form of the MR is shed into the serum, which is generated through proteolytic cleavage of the membrane-bound receptor.
c128 cso30:c:InputProcess connector
c129 cso30:c:OutputProcess connector
p44_propro_p44
PMID: 18160296, 16213021
Similar to MBP, these collectins have been proposed to bind directly to cellular receptors, including C1q receptor (C1qRp), signal-regulating protein alpha (SIRPalpha), calreticulin and CD14.
c114 cso30:c:InputProcess connector
c132 cso30:c:InputProcess connector
c136 cso30:c:OutputProcess connector
p45_propro_p45
PMID: 18160296, 16213021
Similar to MBP, these collectins have been proposed to bind directly to cellular receptors, including C1q receptor (C1qRp), signal-regulating protein alpha (SIRPalpha), calreticulin and CD14.
c115 cso30:c:InputProcess connector
c133 cso30:c:InputProcess connector
c137 cso30:c:OutputProcess connector
p46_propro_p46
PMID: 18160296, 16213021
Similar to MBP, these collectins have been proposed to bind directly to cellular receptors, including C1q receptor (C1qRp), signal-regulating protein alpha (SIRPalpha), calreticulin and CD14.
c134 cso30:c:InputProcess connector
c140 cso30:c:InputProcess connector
c138 cso30:c:OutputProcess connector
p47_propro_p47
PMID: 18160296, 16213021
Similar to MBP, these collectins have been proposed to bind directly to cellular receptors, including C1q receptor (C1qRp), signal-regulating protein alpha (SIRPalpha), calreticulin and CD14.
c135 cso30:c:InputProcess connector
c141 cso30:c:InputProcess connector
c139 cso30:c:OutputProcess connector
p48_propro_p48
PMID: 18160296, 12524383, 16166590
The identity of the MBL receptor(s) is controversial, although a number have been proposed, including calreticulin, complement receptor 1 and the integrin.
c67 cso30:c:InputProcess connector
c68 cso30:c:InputProcess connector
c69 cso30:c:OutputProcess connector
p49_propro_p49
PMID: 18160296, 12524383, 16166590
The identity of the MBL receptor(s) is controversial, although a number have been proposed, including calreticulin, complement receptor 1 and the integrin.
c70 cso30:c:InputProcess connector
c150 cso30:c:InputProcess connector
c71 cso30:c:OutputProcess connector
p50_propro_p50
PMID: 18160296, 12524383, 16166590
The identity of the MBL receptor(s) is controversial, although a number have been proposed, including calreticulin, complement receptor 1 and the integrin.
c147 cso30:c:InputProcess connector
c148 cso30:c:InputProcess connector
c149 cso30:c:OutputProcess connector
TLR: TLR_enti_MO000019395
TLR: TLR
MyD88_enti_MO000016573
MyD88
TRIF_enti_MO000041125
TRIF
NF-kappaB_enti_MO000000058
NF-kappaB
IRF-3_enti_MO000007694
IRF-3
TLR liagnd_enti_e5
TLR liagnd
TLR ligand: TLR: TLR_enti_e6
TLR ligand: TLR: TLR
TLR ligand: TLR: TLR: MyD88_enti_e11
TLR ligand: TLR: TLR: MyD88
TLR ligand: TLR: TLR: TRIF_enti_e12
TLR ligand: TLR: TLR: TRIF
NF-kappaB {activated}_enti_e13
NF-kappaB {activated}
IRF-3 {activated}_enti_e14
IRF-3 {activated}
mannose receptor_enti_e15
mannose receptor
mannose_enti_e16
mannose
fucose_enti_e17
fucose
N-acetyl glucosamine_enti_e18
N-acetyl glucosamine
mannose: mannose receptor_enti_e19
mannose: mannose receptor
fucose: mannose receptor_enti_e20
fucose: mannose receptor
N-acetyl glucosamine: mannose receptor_enti_e21
N-acetyl glucosamine: mannose receptor
mannan_enti_e22
mannan
DC-SIGN_enti_MO000042415
DC-SIGN
mannan: DC-SIGN_enti_e23
mannan: DC-SIGN
IL-12 p40_enti_G010657
IL-12 p40
IL-12_enti_MO000017265
IL-12
mannose receptor ligand_enti_e24
mannose receptor ligand
mannose receptor ligand: mannose receptor_enti_e25
mannose receptor ligand: mannose receptor
IL-8_enti_MO000017264
IL-8
IL8_enti_e26
IL8
IL-1beta_enti_G010389
IL-1beta
IL-1beta_enti_MO000016597
IL-1beta
IL-6_enti_G010262
IL-6
IL-6_enti_MO000007384
IL-6
GM-CSF_enti_G010220
GM-CSF
GM-CSF_enti_MO000000099
GM-CSF
TNF-alpha_enti_G010329
TNF-alpha
TNF-alpha_enti_MO000000289
TNF-alpha
Dectin-1_enti_e27
Dectin-1
beta1, 3-glucans: Dectin-1_enti_e28
beta1, 3-glucans: Dectin-1
beta1, 3-glucans_enti_e29
beta1, 3-glucans
MIP-2_enti_e30
MIP-2
MIP-2_enti_e31
MIP-2
IL-2_enti_G010229
IL-2
IL-2_enti_MO000017061
IL-2
IL-23_enti_e32
IL-23
IL-23_enti_e33
IL-23
Syk_enti_MO000008301
Syk
CARD9 {activated}_enti_MO000044196
CARD9 {activated}
Syk: beta1, 3-glucans: Dectin-1_enti_e34
Syk: beta1, 3-glucans: Dectin-1
CARD9_enti_e35
CARD9
PLA2_enti_MO000016723
PLA2
CoxII_enti_MO000069544
CoxII
PLA2 {activated}_enti_e36
PLA2 {activated}
CoxII {activated}_enti_e37
CoxII {activated}
Dectin-2_enti_e38
Dectin-2
fucose: Dectin-2_enti_e39
fucose: Dectin-2
mannose: Dectin-2_enti_e40
mannose: Dectin-2
Ca_enti_e41
Ca
mannan: DC-SIGN tetratmer_enti_e42
mannan: DC-SIGN tetratmer
DC-SIGN (murine)_enti_e43
DC-SIGN (murine)
fungal particle_enti_e44
fungal particle
fungal particle: DC-SIGN (murine)_enti_e45
fungal particle: DC-SIGN (murine)
Raf kianse_enti_e46
Raf kianse
Raf kinase (activated}_enti_e47
Raf kinase (activated}
IL10_enti_G011345
IL10
SIRPalpha_enti_e48
SIRPalpha
C1qRp_enti_e63
C1qRp
calreticulin_enti_MO000017520
calreticulin
CD14_enti_MO000018132
CD14
C1qRp: SP-A_enti_e64
C1qRp: SP-A
SIRPalpha: SP-A_enti_e65
SIRPalpha: SP-A
calreticulin: SP-A_enti_e66
calreticulin: SP-A
CD14: SP-A_enti_e67
CD14: SP-A
cytokines_enti_MO000019387
cytokines
cytokines_enti_e68
cytokines
SP-A_enti_e69
SP-A
SP-D_enti_e70
SP-D
mannose receptor_enti_e71
mannose receptor
C1qRp: SP-D_enti_e49
C1qRp: SP-D
SIRPalpha: SP-D_enti_e72
SIRPalpha: SP-D
calreticulin: SP-D_enti_e73
calreticulin: SP-D
CD14: SP-D_enti_e74
CD14: SP-D
alpha2 beta1_enti_MO000019699
alpha2 beta1
MBL_enti_MO000062069
MBL
CR1_enti_MO000070528
CR1
MBL: alpha2 beta1_enti_e75
MBL: alpha2 beta1
MBL: CR1_enti_e76
MBL: CR1
MBL: calreticulin_enti_e77
MBL: calreticulin