PMID: 1315450, 2361453, 1647300 Our time-course studies show that plasma corticosterone levels are already maximally elevated 1 hour after endotoxin administration.

PMID: 1315450, 3543052 The most predominant cytokines released by macrophages after endotoxin administration are interleukin-1 (ILl) and tumour necrosis factor (TNF) which in turn induce other cytokines like interleukin 6.

PMID: 1315450, 3543052 The most predominant cytokines released by macrophages after endotoxin administration are interleukin-1 (ILl) and tumour necrosis factor (TNF) which in turn induce other cytokines like interleukin 6.

PMID: 1315450, 3543052 The most predominant cytokines released by macrophages after endotoxin administration are interleukin-1 (ILl) and tumour necrosis factor (TNF) which in turn induce other cytokines like interleukin 6.

PMID: 1315450, 2361453, 2845968, 2542010 Injections of recombinant preparations of these 3 cytokines can induce the release of ACTH and corcorticosterone, by an action involving the release of CRF from the hypothalamus.

PMID: 1315450, 2361453, 2845968, 2542010 Injections of recombinant preparations of these 3 cytokines can induce the release of ACTH and corcorticosterone, by an action involving the release of CRF from the hypothalamus.

PMID: 1315450, 2361453, 2845968, 2542010 Injections of recombinant preparations of these 3 cytokines can induce the release of ACTH and corcorticosterone, by an action involving the release of CRF from the hypothalamus.

PMID: 1315450, 2361453, 2845968, 2542010 Injections of recombinant preparations of these 3 cytokines can induce the release of ACTH and corcorticosterone, by an action involving the release of CRF from the hypothalamus.

PMID: 1315450, 2361453, 2845968, 2542010 Injections of recombinant preparations of these 3 cytokines can induce the release of ACTH and corcorticosterone, by an action involving the release of CRF from the hypothalamus.

PMID: 1315450, 2361453, 2845968, 2542010 Injections of recombinant preparations of these 3 cytokines can induce the release of ACTH and corcorticosterone, by an action involving the release of CRF from the hypothalamus.

PMID: 1315450, 2361453, 2845968, 2542010 Injections of recombinant preparations of these 3 cytokines can induce the release of ACTH and corcorticosterone, by an action involving the release of CRF from the hypothalamus.

PMID: 1315450, 2555127, 4719686, 3330674 endotoxin administration elevates plasma ACTH and glucocorticoid levels in a variety of species including man.

PMID: 1315450 endotoxin induces the activation of the complement system resulting in the generation of C3a and CSa, which in turn can degranulate mast cells resulting in the release of vasoactive substances, such as histamine.

PMID: 1315450 endotoxin induces the activation of the complement system resulting in the generation of C3a and CSa, which in turn can degranulate mast cells resulting in the release of vasoactive substances, such as histamine.

PMID: 1315450 endotoxin induces the activation of the complement system resulting in the generation of C3a and CSa, which in turn can degranulate mast cells resulting in the release of vasoactive substances, such as histamine.

PMID: 1315450, 3543052 The most predominant cytokines released by macrophages after endotoxin administration are interleukin-1 (ILl) and tumour necrosis factor (TNF) which in turn induce other cytokines like interleukin 6.

PMID: 1315450, 3543052 The most predominant cytokines released by macrophages after endotoxin administration are interleukin-1 (ILl) and tumour necrosis factor (TNF) which in turn induce other cytokines like interleukin 6.

PMID: 1315450, 3543052 The most predominant cytokines released by macrophages after endotoxin administration are interleukin-1 (ILl) and tumour necrosis factor (TNF) which in turn induce other cytokines like interleukin 6.

PMID: 1315450, 3543052 The most predominant cytokines released by macrophages after endotoxin administration are interleukin-1 (ILl) and tumour necrosis factor (TNF) which in turn induce other cytokines like interleukin 6.

PMID: 1315450, 3543052 The most predominant cytokines released by macrophages after endotoxin administration are interleukin-1 (ILl) and tumour necrosis factor (TNF) which in turn induce other cytokines like interleukin 6.

PMID: 1315450, 3543052 The most predominant cytokines released by macrophages after endotoxin administration are interleukin-1 (ILl) and tumour necrosis factor (TNF) which in turn induce other cytokines like interleukin 6.

PMID: 1315450, 3543052 The most predominant cytokines released by macrophages after endotoxin administration are interleukin-1 (ILl) and tumour necrosis factor (TNF) which in turn induce other cytokines like interleukin 6.