_enti_e7
_enti_e8
_enti_e1
_enti_e9
_enti_e10
_enti_e4
_enti_e2
_enti_e3
_enti_e55
_enti_e59
_enti_e53
_enti_e54
_enti_e56
_enti_e51
_enti_e52
_enti_e50
_enti_e57
_enti_e58
_enti_e61
_enti_e60
_enti_e62
g1_fact_g1
g1_fact_g2
g2_fact_g12
g2_fact_g13
g1_fact_g14
p1_propro_p1
PMID: 16920490
IFN-gamma binds to the IFN-gamma receptor.
c1 cso30:c:InputProcess connector
c2 cso30:c:InputProcess connector
c3 cso30:c:OutputProcess connector
p2_propro_p2
PMID: 16920490, 11964313, 12811837,7999637, 11672593, 12831455
IFNγ stimulation induced Tlr2, Tlr4, and Tlr6 mRNAs, upregulated expression of TLR2 and TLR4 protein at the cell surface, and increased resulting LPS-binding ability of macrophages
c4 cso30:c:InputAssociation connector
c7 cso30:c:OutputProcess connector
p3_propro_p3
PMID: 16920490, 12831455, 11672593, 7999637, 12811837, 11964313
IFNγ stimulation induced Tlr2, Tlr4, and Tlr6 mRNAs, upregulated expression of TLR2 and TLR4 protein at the cell surface, and increased resulting LPS-binding ability of macrophages
c5 cso30:c:InputAssociation connector
c8 cso30:c:OutputProcess connector
p4_propro_p4
PMID: 16920490, 11964313, 12811837, 7999637, 1167259
IFNγ stimulation induced Tlr2, Tlr4, and Tlr6 mRNAs, upregulated expression of TLR2 and TLR4 protein at the cell surface, and increased resulting LPS-binding ability of macrophages
c6 cso30:c:InputAssociation connector
c9 cso30:c:OutputProcess connector
p5_propro_p5
PMID: 16920490, 12831455, 11672593, 7999637, 12811837, 11964313
IFNγ stimulation induced Tlr2, Tlr4, and Tlr6 mRNAs, upregulated expression of TLR2 and TLR4 protein at the cell surface, and increased resulting LPS-binding ability of macrophages
c10 cso30:c:InputProcess connector
c14 cso30:c:InputAssociation connector
c12 cso30:c:OutputProcess connector
p7_propro_p7
PMID: 16920490, 11964313, 12811837, 7999637, 11672593, 12831455
IFNγ stimulation induced Tlr2, Tlr4, and Tlr6 mRNAs, upregulated expression of TLR2 and TLR4 protein at the cell surface, and increased resulting LPS-binding ability of macrophages
c16 cso30:c:InputProcess connector
c42 cso30:c:OutputProcess connector
p8_propro_p8
PMID: 16920490, 11964313, 12811837, 7999637, 11672593, 12831455
IFNγ stimulation induced Tlr2, Tlr4, and Tlr6 mRNAs, upregulated expression of TLR2 and TLR4 protein at the cell surface, and increased resulting LPS-binding ability of macrophages
c17 cso30:c:InputProcess connector
c48 cso30:c:OutputProcess connector
p9_propro_p9
PMID: 16920490, 1698311
In the case of LPS, efficient ligand recognition requires the signalling receptor TLR4, as well as the CD14 co-receptor
c18 cso30:c:InputProcess connector
c19 cso30:c:InputProcess connector
c20 cso30:c:OutputProcess connector
p10_propro_p10
PMID: 16920490, 1698311, 10359581
In the case of LPS, efficient ligand recognition requires the signalling receptor TLR4, as well as the CD14 co-receptor (Wright et al., 1990) and MD-2 accessory molecule
c21 cso30:c:InputProcess connector
c76 cso30:c:InputProcess connector
c23 cso30:c:OutputProcess connector
p11_propro_p11
PMID: 16920490, 1698311, 10359581
n the case of LPS, efficient ligand recognition requires the signalling receptor TLR4, as well as the CD14 co-receptor (Wright et al., 1990) and MD-2 accessory molecule
c24 cso30:c:InputProcess connector
c25 cso30:c:InputProcess connector
c26 cso30:c:OutputProcess connector
p12_propro_p12
PMID: 16920490, 14993454
Full signal transduction requires a number of signalling adaptors, including MyD88 and the adaptors of the MyD88-independent pathway, TRAM (also called TIRP, TICAM2) and TRIF (also known as TICAM1) (reviewed in Vogel et al., 2003)
c27 cso30:c:InputProcess connector
c28 cso30:c:InputProcess connector
c29 cso30:c:OutputProcess connector
p13_propro_p13
PMID: 16920490, 14993454
Full signal transduction requires a number of signalling adaptors, including MyD88 and the adaptors of the MyD88-independent pathway, TRAM (also called TIRP, TICAM2) and TRIF (also known as TICAM1) (reviewed in Vogel et al., 2003)
c30 cso30:c:InputProcess connector
c31 cso30:c:InputProcess connector
c32 cso30:c:OutputProcess connector
p14_propro_p14
PMID: 16920490, 14993454
Full signal transduction requires a number of signalling adaptors, including MyD88 and the adaptors of the MyD88-independent pathway, TRAM (also called TIRP, TICAM2) and TRIF (also known as TICAM1) (reviewed in Vogel et al., 2003)
c33 cso30:c:InputProcess connector
c34 cso30:c:InputProcess connector
c35 cso30:c:OutputProcess connector
p15_propro_p15
PMID: 16920490, 11130078
CpG DNA signalling is mediated by the TLR9 signalling receptor
c36 cso30:c:InputProcess connector
c37 cso30:c:InputProcess connector
c38 cso30:c:OutputProcess connector
p16_propro_p16
PMID: 16920490, 11130078
CpG DNA signalling is mediated by the TLR9 signalling receptor (Hemmi et al., 2000), and unlike TLR4, the MyD88 signalling adaptor mediates all known downstream responses (Schnare et al., 2000).
c39 cso30:c:InputProcess connector
c40 cso30:c:InputProcess connector
c41 cso30:c:OutputProcess connector
p17_propro_p17
PMID: 16920490, 15928677
LPS induces expression of negative regulators of key adaptor/signalling molecules (e.g. IRAK-M and SOCS1 that target IRAKs, ST2L that sequesters MyD88 and MAL) (Liew et al., 2005).
c44 cso30:c:InputAssociation connector
c45 cso30:c:OutputProcess connector
p18_propro_p18
PMID: 16920490, 15928677, 11870615, 12811837, 10453004
LPS induces expression of negative regulators of key adaptor/signalling molecules (e.g. IRAK-M and SOCS1 that target IRAKs, ST2L that sequesters MyD88 and MAL) (Liew et al., 2005).
Both LPS and IFNγ induced expression of these SOCS proteins (SOCS1 and SOCS3), and LPS pre-treatment inhibited some functions of IFNγ signalling via the activities of these proteins (Crespo et al., 2002; Dalpke et al., 2003; Stoiber et al., 1999
c47 cso30:c:InputAssociation connector
c46 cso30:c:OutputProcess connector
p19_propro_p19
PMID: 16920490
Induction of Tlr9 mRNA by IFNγ in BMM was largely dependent on the presence of CSF-1 that suppressed Tlr9 expression (manuscript in preparation).
c49 cso30:c:InputAssociation connector
c53 cso30:c:InputInhibitor connector
c50 cso30:c:OutputProcess connector
p20_propro_p20
PMID: 16920490
Induction of Tlr9 mRNA by IFNγ in BMM was largely dependent on the presence of CSF-1 that suppressed Tlr9 expression (manuscript in preparation).
c51 cso30:c:InputProcess connector
c52 cso30:c:OutputProcess connector
p21_propro_p21
PMID: 16920490, 10725699
LPS downregulates surface expression of the signalling receptor TLR4, and its accessory molecule, MD-2 (Nomura et al., 2000).
c43 cso30:c:InputProcess connector
c55 cso30:c:InputInhibitor connector
c54 cso30:c:OutputProcess connector
p22_propro_p22
PMID: 16920490, 10725699
LPS downregulates surface expression of the signalling receptor TLR4, and its accessory molecule, MD-2 (Nomura et al., 2000).
c56 cso30:c:InputProcess connector
c58 cso30:c:InputInhibitor connector
c57 cso30:c:OutputProcess connector
p23_propro_p23
PMID: 16920490, 11964313, 15324355, 12761135,12831455
Numerous reports document the IFNγ-dependent induction of the CD14 co-receptor and MD-2 accessory molecule, which aid in LPS signalling
c59 cso30:c:InputAssociation connector
c60 cso30:c:OutputProcess connector
p24_propro_p24
PMID: 16920490, 12831455, 12761135, 15324355 ,11964313
Numerous reports document the IFNγ-dependent induction of the CD14 co-receptor and MD-2 accessory molecule, which aid in LPS signalling
c61 cso30:c:InputAssociation connector
c62 cso30:c:OutputProcess connector
p25_propro_p25
PMID: 16920490, 11964313, 15324355, 12761135, 12831455
12032143
Additionally, IFNγ upregulated the expression of MyD88 (Bosisio et al., 2002; Mochizuki et al., 2004; Tamai et al., 2003) and IRAK1 (Adib-Conquy and Cavaillon, 2002), which participate in TLR signalling pathways.
c63 cso30:c:InputAssociation connector
c64 cso30:c:OutputProcess connector
p26_propro_p26
PMID: 16920490,12032143
Additionally, IFNγ upregulated the expression of MyD88 and IRAK1
c65 cso30:c:InputAssociation connector
c66 cso30:c:OutputProcess connector
p27_propro_p27
PMID: 16920490, 12811837, 10453004, 11870615
Both LPS and IFNγ induced expression of these SOCS proteins (SOCS1 and SOCS3), and LPS pre-treatment inhibited some functions of IFNγ signalling via the activities of these proteins (Crespo et al., 2002; Dalpke et al., 2003; Stoiber et al., 1999).
c67 cso30:c:InputAssociation connector
c68 cso30:c:OutputProcess connector
p28_propro_p28
PMID: 16920490, 11870615, 10453004, 12811837
Both LPS and IFNγ induced expression of these SOCS proteins (SOCS1 and SOCS3), and LPS pre-treatment inhibited some functions of IFNγ signalling via the activities of these proteins (Crespo et al., 2002; Dalpke et al., 2003; Stoiber et al., 1999).
c69 cso30:c:InputAssociation connector
c70 cso30:c:OutputProcess connector
p29_propro_p29
PMID: 16920490, 10453004, 12811837, 11870615
Both LPS and IFNγ induced expression of these SOCS proteins (SOCS1 and SOCS3), and LPS pre-treatment inhibited some functions of IFNγ signalling via the activities of these proteins (Crespo et al., 2002; Dalpke et al., 2003; Stoiber et al., 1999
c71 cso30:c:InputAssociation connector
c72 cso30:c:OutputProcess connector
p30_propro_p30
PMID: 16920490, 15928677
LPS induces expression of negative regulators of key adaptor/signalling molecules (e.g. IRAK-M and SOCS1 that target IRAKs, ST2L that sequesters MyD88 and MAL) (Liew et al., 2005).
c73 cso30:c:InputAssociation connector
c74 cso30:c:OutputProcess connector
p33_propro_p33
PMID: 16920490, 9864217
IFNγ pre-treatment of RAW264.7 cells promoted LPS-induced NF-κB activation and DNA binding kinetics, as well as causing more rapid degradation of the NF-κB inhibitor, IκBα (Held et al., 1999)
c79 cso30:c:InputProcess connector
c80 cso30:c:OutputProcess connector
p34_propro_p34
PMID: 16920490, 9864217
IFNγ pre-treatment of RAW264.7 cells promoted LPS-induced NF-κB activation and DNA binding kinetics, as well as causing more rapid degradation of the NF-κB inhibitor, IκBα (Held et al., 1999)
c81 cso30:c:InputProcess connector
c82 cso30:c:InputProcess connector
c84 cso30:c:InputAssociation connector
c83 cso30:c:OutputProcess connector
p36_propro_p36
PMID: 16920490
IFNγ also influenced the activity of another key LPS-induced transcription factor, AP-1, in human monocytes.
c90 cso30:c:InputAssociation connector
c91 cso30:c:OutputProcess connector
p37_propro_p37
PMID: 16920490, 11972023, 10975834, 9649436
In the case of TLR4, LPS treatment following IFNγ exposure increased the percentage of STAT1 molecules phosphorylated on both Y701 and S727, and subsequent STAT1 DNA-binding activity relative to IFNγ treatment alone
c93 cso30:c:InputProcess connector
c120 cso30:c:InputAssociation connector
c94 cso30:c:OutputProcess connector
p38_propro_p38
PMID: 16920490, 12667213, 9568729
IFNγ signalling induced Inos mRNA via STAT1, but induction was maximal only when the Inos promoter NF-κB sites were occupied following TLR ligation
c95 cso30:c:InputAssociation connector
c96 cso30:c:OutputProcess connector
p39_propro_p39
PMID: 16920490, 2498530
IFN-gamma stimulation induces Ifn-beta mRNA.
c97 cso30:c:InputAssociation connector
c98 cso30:c:OutputProcess connector
p31_propro_p31
PMID: 16920490, 12811837, 12686553
Signalling initiated by a number of TLR agonists (e.g. LPS, CpG DNA, lipotechoic acid) induced STAT1 S727 phosphorylation, via activation of p38 MAPK pathways (
c99 cso30:c:InputProcess connector
c100 cso30:c:InputProcess connector
c101 cso30:c:OutputProcess connector
p42_propro_p42
PMID: 16920490, 12811837, 12686553
Signalling initiated by a number of TLR agonists (e.g. LPS, CpG DNA, lipotechoic acid) induced STAT1 S727 phosphorylation, via activation of p38 MAPK pathways
c111 cso30:c:InputAssociation connector
c116 cso30:c:InputProcess connector
c119 cso30:c:OutputProcess connector
p43_propro_p43
PMID: 16920490, 12811837, 12686553
Signalling initiated by a number of TLR agonists (e.g. LPS, CpG DNA, lipotechoic acid) induced STAT1 S727 phosphorylation, via activation of p38 MAPK pathways
c108 cso30:c:InputAssociation connector
c109 cso30:c:InputProcess connector
c110 cso30:c:OutputProcess connector
p44_propro_p44
PMID: 16920490, 12811837, 12686553
Signalling initiated by a number of TLR agonists (e.g. LPS, CpG DNA, lipotechoic acid) induced STAT1 S727 phosphorylation, via activation of p38 MAPK pathways
c105 cso30:c:InputAssociation connector
c106 cso30:c:InputProcess connector
c107 cso30:c:OutputProcess connector
p45_propro_p45
PMID: 16920490, 12811837, 12686553
Signalling initiated by a number of TLR agonists (e.g. LPS, CpG DNA, lipotechoic acid) induced STAT1 S727 phosphorylation, via activation of p38 MAPK pathways
c92 cso30:c:InputProcess connector
c102 cso30:c:InputAssociation connector
c104 cso30:c:OutputProcess connector
p46_propro_p46
PMID: 16920490, 10975834, 9649436
In the case of TLR4, LPS treatment following IFNγ exposure increased the percentage of STAT1 molecules phosphorylated on both Y701 and S727, and subsequent STAT1 DNA-binding activity relative to IFNγ treatment alone
c121 cso30:c:InputProcess connector
c122 cso30:c:OutputProcess connector
p47_propro_p47
PMID: 16920490, 10975834, 9649436
In the case of TLR4, LPS treatment following IFNγ exposure increased the percentage of STAT1 molecules phosphorylated on both Y701 and S727, and subsequent STAT1 DNA-binding activity relative to IFNγ treatment alone
c123 cso30:c:InputProcess connector
c11 cso30:c:InputProcess connector
c125 cso30:c:OutputProcess connector
p49_propro_p49
PMID: 16920490, 16816106
Recent studies from our laboratory showed that Hdac1 mRNA was induced by LPS in BMM and that HDACs acted as negative feedback regulators of a sub-set of LPS-inducible genes, including Cox2
c129 cso30:c:InputAssociation connector
c130 cso30:c:OutputProcess connector
p50_propro_p50
PMID: 16920490, 16816106
Recent studies from our laboratory showed that Hdac1 mRNA was induced by LPS in BMM and that HDACs acted as negative feedback regulators of a sub-set of LPS-inducible genes, including Cox2
c131 cso30:c:InputProcess connector
c132 cso30:c:OutputProcess connector
p51_propro_p51
PMID: 16920490, 14645718, 16481475
Further, STAT1 and HDAC1 physically interact (Nusinzon and Horvath, 2003) and STAT1 is an acetylated protein
c133 cso30:c:InputProcess connector
c134 cso30:c:InputProcess connector
c135 cso30:c:OutputProcess connector
p52_propro_p52
PMID: 16920490, 16816106
Recent studies from our laboratory showed that Hdac1 mRNA was induced by LPS in BMM and that HDACs acted as negative feedback regulators of a sub-set of LPS-inducible genes, including Cox2
c136 cso30:c:InputAssociation connector
c138 cso30:c:InputInhibitor connector
c137 cso30:c:OutputProcess connector
p53_propro_p53
PMID: 14920490, 16164016
Both IFNγ and LPS induce Icsbp mRNA in macrophages, but induction is dependent on the presence of CSF-1
Coupled with the studies from our laboratory described above, demonstrating that ICSBP expression was modulated by both IFNγ (positively) and CSF-1 (negatively), this implies that ICSBP functions to integrate CSF-1 and IFNγ signalling directly into the TLR signalling pathway, by directly modulating TRAF6 function.
c139 cso30:c:InputAssociation connector
c143 cso30:c:InputInhibitor connector
c141 cso30:c:OutputProcess connector
p54_propro_p54
PMID: 16920490, 16164016
Both IFNγ and LPS induce Icsbp mRNA in macrophages, but induction is dependent on the presence of CSF-1
c140 cso30:c:InputAssociation connector
c86 cso30:c:InputInhibitor connector
c142 cso30:c:OutputProcess connector
p55_propro_p55
PMID:16920490, 8456286, 16484229
S148-phosphorylated PU.1 is able to interact with ICSBP upon composite PU.1/IRF sites to potentiate PU.1-dependent transactivation
the Ets family member PU.l is phosphorylated by LPS and interacts with IFNγ-induced ICSBP
ICSBP may participate more directly in the TLR signalling pathway, via interaction with TRAF6
c144 cso30:c:InputProcess connector
c145 cso30:c:OutputProcess connector
p56_propro_p56
PMID: 14920490, 16484229
In addition to its function as a transcription factor, a recent article suggested that ICSBP may participate more directly in the TLR signalling pathway, via interaction with TRAF6
c146 cso30:c:InputProcess connector
c147 cso30:c:InputProcess connector
c148 cso30:c:OutputProcess connector
p57_propro_p57
PMID: 16920490, 7609733
PU.1 is phosphorylated at S148 in response to LPS, and phosphorylation is necessary for the full spectrum of macrophage responses to LPS (e.g. induction of IL-1β (Buras et al., 1995)
c150 cso30:c:InputProcess connector
c112 cso30:c:InputAssociation connector
c151 cso30:c:OutputProcess connector
p58_propro_p58
PMID: 16920490, 8456286,1729611
S148-phosphorylated PU.1 is able to interact with ICSBP upon composite PU.1/IRF sites to potentiate PU.1-dependent transactivation
the Ets family member PU.l is phosphorylated by LPS and interacts with IFNγ-induced ICSBP
c152 cso30:c:InputProcess connector
c153 cso30:c:InputProcess connector
c154 cso30:c:OutputProcess connector
p35_propro_p35
PMID: 16920490, 9864217
IFNγ pre-treatment of RAW264.7 cells promoted LPS-induced NF-κB activation and DNA binding kinetics, as well as causing more rapid degradation of the NF-κB inhibitor, IκBα
c85 cso30:c:InputProcess connector
c87 cso30:c:InputAssociation connector
c75 cso30:c:OutputProcess connector
p32_propro_p32
PMID: 16920490, 15928677
LPS induces expression of negative regulators of key adaptor/signalling molecules (e.g. IRAK-M and SOCS1 that target IRAKs, ST2L that sequesters MyD88 and MAL) (Liew et al., 2005).
c22 cso30:c:InputAssociation connector
c77 cso30:c:OutputProcess connector
p40_propro_p40
PMID: 16920490, 15928677
LPS induces expression of negative regulators of key adaptor/signalling molecules (e.g. IRAK-M and SOCS1 that target IRAKs, ST2L that sequesters MyD88 and MAL) (Liew et al., 2005).
c78 cso30:c:InputAssociation connector
c113 cso30:c:InputInhibitor connector
c88 cso30:c:OutputProcess connector
p34_propro_p41
PMID: 16920490, 9864217
IFNγ pre-treatment of RAW264.7 cells promoted LPS-induced NF-κB activation and DNA binding kinetics, as well as causing more rapid degradation of the NF-κB inhibitor, IκBα (Held et al., 1999)
c114 cso30:c:InputProcess connector
c115 cso30:c:InputProcess connector
c118 cso30:c:InputAssociation connector
c117 cso30:c:OutputProcess connector
p37_propro_p48
PMID: 16920490, 11972023, 10975834, 9649436
STAT1 is phosphorylated at both sites following IFNγ exposure; the IFNγ receptor/JAK complex directly mediates Y701 phosphorylation, whereas S727 phosphorylation occurs via a separate pathway involving Ca(2+)/calmodulin-dependent kinase II
c89 cso30:c:InputProcess connector
c127 cso30:c:InputAssociation connector
c126 cso30:c:OutputProcess connector
p35_propro_p59
PMID: 16920490, 9864217
IFNγ pre-treatment of RAW264.7 cells promoted LPS-induced NF-κB activation and DNA binding kinetics, as well as causing more rapid degradation of the NF-κB inhibitor, IκBα
c103 cso30:c:InputProcess connector
c149 cso30:c:InputAssociation connector
c128 cso30:c:OutputProcess connector
IFN-gamma_enti_e5
IFN-gamma
IFN-gamma receptor_enti_e6
IFN-gamma receptor
IFN-gamma: IFN-gamma receptor_enti_e11
IFN-gamma: IFN-gamma receptor
Tlr2_enti_e12
Tlr2
Tlr4_enti_e13
Tlr4
Tlr6_enti_e14
Tlr6
TLR2_enti_e15
TLR2
TLR4_enti_e16
TLR4
LPS_enti_e17
LPS
CD14_enti_e18
CD14
CD14:LPS_enti_e19
CD14:LPS
TLR4_enti_e20
TLR4
TLR4:MD-2_enti_e22
TLR4:MD-2
TLR4:MD-2:CD14:LPS_enti_e23
TLR4:MD-2:CD14:LPS
MyD88_enti_e24
MyD88
TLR4:MD-2:CD14:LPS:MyD88_enti_e25
TLR4:MD-2:CD14:LPS:MyD88
TRAM_enti_e26
TRAM
TLR4:MD-2:CD14:LPS:TRAM_enti_e27
TLR4:MD-2:CD14:LPS:TRAM
TRIF_enti_e28
TRIF
TLR4:MD-2:CD14:TRIF_enti_e29
TLR4:MD-2:CD14:TRIF
CpG DNA_enti_e30
CpG DNA
TLR9_enti_e31
TLR9
TLR9:CpGDNA_enti_e32
TLR9:CpGDNA
MyD88:TLR9:CpGDNA_enti_e33
MyD88:TLR9:CpGDNA
IRAK-M_enti_e34
IRAK-M
SOCS1_enti_e35
SOCS1
TLR2_enti_e36
TLR2
Tlr9_enti_e37
Tlr9
CSF-1_enti_e39
CSF-1
MD-2_enti_e40
MD-2
MD-2_enti_e41
MD-2
CD14_enti_e42
CD14
myd88_enti_e43
myd88
IRAK1_enti_e44
IRAK1
socs3_enti_e45
socs3
ST2L_enti_e46
ST2L
NF-KappB:IKBalpha_enti_e47
NF-KappB:IKBalpha
NFKappaB{active}_enti_e48
NFKappaB{active}
NFKappB{active}_enti_e49
NFKappB{active}
DNA:NFKappaB_enti_e63
DNA:NFKappaB
DNA_enti_e64
DNA
AP-1_enti_e66
AP-1
STAT1_enti_e67
STAT1
STAT1{p}_enti_e68
STAT1{p}
Inos_enti_e69
Inos
ifnbeta_enti_e70
ifnbeta
Lipotechoi acid_enti_e71
Lipotechoi acid
TLR2:Lipotechoic acid_enti_e72
TLR2:Lipotechoic acid
p38 MAPK_enti_e73
p38 MAPK
p38 MAPK{active}_enti_e74
p38 MAPK{active}
STAT1{p}_enti_e75
STAT1{p}
DNA:STAT1_enti_e77
DNA:STAT1
STAT1{ace}_enti_e78
STAT1{ace}
Hdac1_enti_e80
Hdac1
STAT1{ace}:HDAC1_enti_e81
STAT1{ace}:HDAC1
HDAC1_enti_e82
HDAC1
cox2_enti_e83
cox2
Icsbp_enti_e84
Icsbp
ICSBP_enti_e85
ICSBP
TRAF6_enti_e86
TRAF6
ICSBP:TRAF6_enti_e87
ICSBP:TRAF6
PU.1_enti_e88
PU.1
PU.1{p}_enti_e89
PU.1{p}
PU.1{p}:ICSBP_enti_e90
PU.1{p}:ICSBP
ST2L_enti_e21
ST2L