_enti_e7
_enti_e8
_enti_e9
_enti_e1
_enti_e10
_enti_e2
_enti_e4
_enti_e3
_enti_e55
_enti_e59
_enti_e53
_enti_e51
_enti_e52
_enti_e56
_enti_e50
_enti_e54
_enti_e61
_enti_e58
_enti_e57
_enti_e62
_enti_e60
g1_fact_g1
g1_fact_g14
g2_fact_g12
g2_fact_g13
p1_propro_p1
PMID: 18249034,15032573
In
particular, mannose- and fucose-specific CLRs, such as
dendritic cell-specific intercellular-grabbing nonintegrin
(DC-SIGN) and the mannose receptor (MR), are well
characterized on the basis of their carbohydrate specificity
and function within the immune system
PMID: 18249034
Within the last few years, numerous C-type lectin
receptors (CLRs), which recognize carbohydrate structures
in a Ca2+-dependent manner, have been identified
c1 cso30:c:InputProcess connector
c2 cso30:c:InputProcess connector
c11 cso30:c:InputAssociation connector
c3 cso30:c:OutputProcess connector
p1_propro_p2
PMID: 18249034,15032573
In
particular, mannose- and fucose-specific CLRs, such as
dendritic cell-specific intercellular-grabbing nonintegrin
(DC-SIGN) and the mannose receptor (MR), are well
characterized on the basis of their carbohydrate specificity
and function within the immune system
PMID: 18249034
Within the last few years, numerous C-type lectin
receptors (CLRs), which recognize carbohydrate structures
in a Ca2+-dependent manner, have been identified
c4 cso30:c:InputProcess connector
c5 cso30:c:InputProcess connector
c10 cso30:c:InputAssociation connector
c6 cso30:c:OutputProcess connector
p1_propro_p3
PMID: 18249034,15032573
In
particular, mannose- and fucose-specific CLRs, such as
dendritic cell-specific intercellular-grabbing nonintegrin
(DC-SIGN) and the mannose receptor (MR), are well
characterized on the basis of their carbohydrate specificity
and function within the immune system
PMID: 18249034
Within the last few years, numerous C-type lectin
receptors (CLRs), which recognize carbohydrate structures
in a Ca2+-dependent manner, have been identified
c7 cso30:c:InputProcess connector
c8 cso30:c:InputProcess connector
c12 cso30:c:InputAssociation connector
c9 cso30:c:OutputProcess connector
p4_propro_p4
PMID: 18249034,3768888
In the 1980s, Kawasaki et al. discovered that rat peritoneal
macrophages expressed a Ca2+-dependent lectin,
distinct from the hepatic ASGP-R, with specificity for
galactose and GalNAc
PMID: 18249034,2358462
Based on its binding properties,
the lectin was isolated and characterized as rat MGL
(rMGL) or macrophage asialoglycoprotein-binding protein
(M-ASGP-BP)
c13 cso30:c:InputProcess connector
c14 cso30:c:InputProcess connector
c15 cso30:c:OutputProcess connector
p5_propro_p5
PMID: 18249034
MGL displays an exclusive
specificity for terminal a- and b-linked GalNAc residues
that naturally occur on glycoproteins or glycosphingolipids
c16 cso30:c:InputProcess connector
c17 cso30:c:InputProcess connector
c18 cso30:c:OutputProcess connector
p5_propro_p6
PMID: 18249034
MGL displays an exclusive
specificity for terminal a- and b-linked GalNAc residues
that naturally occur on glycoproteins or glycosphingolipids
c19 cso30:c:InputProcess connector
c20 cso30:c:InputProcess connector
c21 cso30:c:OutputProcess connector
p7_propro_p7
PMID: 18249034,17195076,15802303
Specific glycans containing terminal GalNAc moieties,
expressed by the human helminth parasite Schistosoma
mansoni as well as by the tumor antigen MUC1 and
the gangliosides GM2 and GD2, were identified as ligands
for MGL
c22 cso30:c:InputProcess connector
c23 cso30:c:InputProcess connector
c24 cso30:c:OutputProcess connector
p7_propro_p8
PMID: 18249034,17195076,15802303
Specific glycans containing terminal GalNAc moieties,
expressed by the human helminth parasite Schistosoma
mansoni as well as by the tumor antigen MUC1 and
the gangliosides GM2 and GD2, were identified as ligands
for MGL
c25 cso30:c:InputProcess connector
c26 cso30:c:InputProcess connector
c27 cso30:c:OutputProcess connector
p7_propro_p9
PMID: 18249034,17195076,15802303
Specific glycans containing terminal GalNAc moieties,
expressed by the human helminth parasite Schistosoma
mansoni as well as by the tumor antigen MUC1 and
the gangliosides GM2 and GD2, were identified as ligands
for MGL
c28 cso30:c:InputProcess connector
c29 cso30:c:InputProcess connector
c30 cso30:c:OutputProcess connector
p7_propro_p10
PMID: 18249034,17195076,15802303
Specific glycans containing terminal GalNAc moieties,
expressed by the human helminth parasite Schistosoma
mansoni as well as by the tumor antigen MUC1 and
the gangliosides GM2 and GD2, were identified as ligands
for MGL
c31 cso30:c:InputProcess connector
c32 cso30:c:InputProcess connector
c33 cso30:c:OutputProcess connector
p11_propro_p11
PMID: 18249034,15262963,7496141
Whereas MGL recognizes only GalNAc
structures, ASGP-R preferentially interacts with tri- or
tetra-antennary glycans containing both galactose or GalNAc residues
c34 cso30:c:InputProcess connector
c35 cso30:c:InputProcess connector
c36 cso30:c:OutputProcess connector
p11_propro_p12
PMID: 18249034,15262963,7496141
Whereas MGL recognizes only GalNAc
structures, ASGP-R preferentially interacts with tri- or
tetra-antennary glycans containing both galactose or GalNAc residues
c37 cso30:c:InputProcess connector
c38 cso30:c:InputProcess connector
c39 cso30:c:OutputProcess connector
p13_propro_p13
PMID: 18249034,15364954
The macrophagespecific
receptor sialoadhesin has been identified as a selfligand
for mMGL1, and it probably regulates the cellular
localization of mMGL1pos cells within LNs
c40 cso30:c:InputProcess connector
c41 cso30:c:InputProcess connector
c42 cso30:c:OutputProcess connector
p14_propro_p14
PMID: 18249034
MGL recognizes all CD45
isoforms, except CD45RO.
c43 cso30:c:InputProcess connector
c44 cso30:c:InputProcess connector
c45 cso30:c:OutputProcess connector
p14_propro_p15
PMID: 18249034
MGL recognizes all CD45
isoforms, except CD45RO.
c46 cso30:c:InputProcess connector
c47 cso30:c:InputProcess connector
c48 cso30:c:OutputProcess connector
p14_propro_p16
PMID: 18249034
MGL recognizes all CD45
isoforms, except CD45RO.
c50 cso30:c:InputProcess connector
c49 cso30:c:InputProcess connector
c51 cso30:c:OutputProcess connector
p14_propro_p17
PMID: 18249034
MGL recognizes all CD45
isoforms, except CD45RO.
c52 cso30:c:InputProcess connector
c53 cso30:c:InputProcess connector
c54 cso30:c:OutputProcess connector
DC-SIGN_enti_e5
DC-SIGN
Mannose_enti_e6
Mannose
DC-SIGN:Mannose_enti_e11
DC-SIGN:Mannose
MR_enti_e12
MR
Mannose:MR_enti_e13
Mannose:MR
Fucose_enti_e14
Fucose
DC-SIGN:Fucose_enti_e15
DC-SIGN:Fucose
Ca2+_enti_e16
Ca2+
rMGL_enti_e17
rMGL
Galactose_enti_e18
Galactose
rMGL:Galactose_enti_e19
rMGL:Galactose
MGL_enti_e20
MGL
Glycoproteins_enti_e21
Glycoproteins
MGL:Glycoproteins_enti_e22
MGL:Glycoproteins
Glycosphingolipids_enti_e23
Glycosphingolipids
MGL:Glycosphingolipids_enti_e24
MGL:Glycosphingolipids
Glycans_enti_e25
Glycans
MGL:Glycans_enti_e26
MGL:Glycans
MUC1_enti_e27
MUC1
MGL:MUC1_enti_e28
MGL:MUC1
GM1_enti_e29
GM1
MGL:GM1_enti_e30
MGL:GM1
GD2_enti_e31
GD2
MGL:GD2_enti_e32
MGL:GD2
ASGP-R_enti_e33
ASGP-R
Tri-antennary glycans_enti_e34
Tri-antennary glycans
ASGP-R:Tri-antennary glycans_enti_e35
ASGP-R:Tri-antennary glycans
tetra-antennary glycans_enti_e36
tetra-antennary glycans
ASGP-R:Tetra-antennary glycans_enti_e37
ASGP-R:Tetra-antennary glycans
sialoadhesin_enti_e38
sialoadhesin
mMGL_enti_e39
mMGL
mMGL:sialoadhesin_enti_e40
mMGL:sialoadhesin
CD45ABC_enti_e41
CD45ABC
MGL:CD45ABC_enti_e42
MGL:CD45ABC
CD45AB_enti_e43
CD45AB
MGL:CD45AB_enti_e44
MGL:CD45AB
CD45BC_enti_e45
CD45BC
MGL:CD45BC_enti_e46
MGL:CD45BC
CD45B_enti_e47
CD45B
CD45B:MGL_enti_e49
CD45B:MGL